Launch Announcement

To read the official announcement, download the press release (pdf).

Funded Projects

 

TechAdvance®

Novel Biosensors for Rapid Determination of Antimicrobial Resistance (AMR)

Rutgers Inventor(s): Yicheng Lu; Pavel Ivanoff Reyes; Steven Zheng; Keyang Yang; Andrew Zheng
Awarded: July 2017

Summary: This project focuses on the development of a highly sensitive, dynamic, rapid, compact and low cost diagnostic sensor technology for monitoring antimicrobial resistance (AMR) and screening antimicrobials that work against resistant strains. This technology is well-suited for AMR detection and has shown the ability to detect the bactericidal effect of ampicillin in E. coli within 10 minutes. In addition, it is also able to detect the growth inhibition effect of miconazole and cytotoxic effect of amphotericin B in yeast within 20-40 minutes.

Market Applications:

  • AMR diagnostic tool/point-of-care diagnostics devices
  • Research assays
  • Drug discovery - high throughput screening of antibiotics, antifungal and anticancer agents

Download: Technology Details (pdf)

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First-in-Class Pan-TAM Inhibitors for Cancer Therapy

Rutgers Inventor(s): William Welsh; Raymond Birge; Youyi Peng; Vladyslav Kholodovych; Stanley Kimani
Awarded: June 2017

Summary: This project focuses on a novel family of small molecule inhibitors that uniquely block TAM receptors (Tyro3, Axl, and Mertk) activation by the endogenous ligand Gas6 in the extracellular domain. In vitro and in vivo tests have demonstrated good anti-cancer activities without discernible toxicity to normal cells/tissues.

Market Applications:

  • Anti-cancer therapeutic
  • Combined with other therapies such as PD-1 immune checkpoint inhibitors
  • Treatment of infectious diseases

Download: Technology Details (pdf)

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A New Catalyst for Generation of Carbon Feedstocks & Fuels from Carbon Dioxide

Rutgers Inventor(s): G. Charles Dismukes; Martha Greenblatt; Anders Laursen; Karin Calvinho
Awarded: June 2017

Summary: This project focuses on transition metal phosphide catalysts used to selectively generate valuable hydrocarbons for fuel or chemical feedstocks for production from CO2. Using renewable electricity for power, the process can be fully sustainable and a carbon neutral technology.

Market Applications:

  • Renewable feedstocks and fuels
  • Methane and ethylene production for the chemical industry
  • CO2 gas to solids via polymeric [CH2O]n (3>n>100), CO2 emissions recycling/mitigation, electrical energy storage;

Download: Technology Details (pdf)

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Tracking the Spread of Cancer with Light for Targeted Treatment

Rutgers Inventor(s): Prabhas Moghe; Richard Riman; Mei-Chee Tan; Dominik Naczynski
Awarded: June 2017

Summary: This project focuses on a new rare earth (RE)-based light-emitting, multifunctional composites for use in a wide variety of biomedical applications including the identification and tracking of cancer. They found that the properties of the composites, in particular their aqueous stability, solubility, biocompatibility, and functionality, can be tailored for specific applications by coating RE nanoparticles with suitable polypeptides, polysaccharides or polymers.

Market Applicaitons:

  • Non-invasive imaging (2 and 3-dimensional)
  • Image-guided interventions (surgical and non-surgical)
  • Drug tracking and delivery
  • Photodynamic therapy

Download: Technology Details (pdf)

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Using Virtual Reality to Help Persons Walk Post Stroke

Rutgers Inventor(s): Judy Deutsch; Robb Gosine
Awarded: May 2017

Summary: This project focuses on a low cost and scalable solution for bringing virtual reality rehabilitation into clinics and patients' homes.

Market Applications:

  • Games were developed to be used at home by patients needing physical therapy
  • First in person with therapist, then can be moved entirely virtual
  • Data collected from the game can be shared with physicians and other therapists
  • Expectation is device and virtual sessions with a therapist will be covered or reimbursed by health insurance

Download: Technology Details (pdf)

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High Performance Graphene-Polymer Matrix Composites

Rutgers Inventor(s): Jennifer Lynch; Tom Nosker; Bernie Kear
Awarded: April 2017

Summary: This project focuses on a scalable method to exfoliate graphite into graphene directly within a molten polymer. The discovery creates the opportunity for the development of lightweight, high performance, next generation materials of extraordinary strength and impact resistance.

Market Applications:

  • Military (lightweight armor, vehicles, small boats, helmets, munitions)
  • Aerospace (UAVs)
  • Transportation (vehicles, small boats)
  • Infrastructure (bridges)
  • Sporting Goods (tennis, golf, hockey, skiing)
  • Packaging (barrier resistant layer)
  • Feedstock for polymer industry

Download: Technology Details (pdf)

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TechXpress

3-D Pre-Vascularized Scaffold for Bone Regeneration

Rutgers Inventor(s): Joseph Freeman; Pankaj Pushpendra Patel
Awarded: June 2017

Summary: This project focuses on a novel bone graft which combines bone-like architecture, ceramic support structures, pre-vascularized tubes, and patient-derived stem cells to create a graft that can immediately support patient weight upon implantation and simultaneously develop new bone and integrated vasculature for short-term and long-term viability and mechanics.

Market Applications:

  • Treatment for bone disorder, loss, and skeletal deficiencies arising from traumatic injury, abnormal development, cancer, and degenerative bone diseases
  • The bone grafting market in the U.S. has an estimated value over $1 billion, making bone second to blood as the most frequently transplanted material
  • Currently no load-bearing, synthetic bone grafts on the market

Download: Technology Details (pdf)

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